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Persistence Barcodes: Reducing Bias in Radiological Analysis

November 20, 2024

Persistence barcodes emerge as a promising tool in radiological analysis, offering a novel approach to reduce bias and uncover hidden patterns in medical imaging.”BUFFALO, NY - November 20, 2024 – A... read more

Oncotarget

Behind the Study: DLL3, ASC1, TTF-1 & Ki-67 in Precision Medicine for SCLC

November 18, 2024

Samuel Silva from the Department of Pathology at Federal University of Ceará in Fortaleza, Brazil, discusses a research paper he co-authored that was published in Oncotarget Volume 15, titled, “Relationship... read more

Oncotarget

Reducing Bias in Radiology with Topological Data Analysis

November 18, 2024

By providing a more comprehensive, robust, and interpretable framework for analyzing medical imaging data, TDA has the potential to enhance the accuracy and fairness of radiological assessments.”BUFFALO, NY - November... read more

Oncotarget

Extracellular Matrix and Tumor-Immune Interactions: Challenges & Opportunities

November 12, 2024

This review explores our current understanding of how ECM geometry influences the behaviors of both immune cells and tumor cells, which in turn impacts treatment efficacy and cancer evolutionary progression.”... read more

Oncotarget

Navigating Bias in AI-Driven Cancer Detection

November 11, 2024

As we eagerly adopt Al models, we need to take a moment to think about the potential biases that they may contain.”BUFFALO, NY - November 11, 2024 – A new editorial... read more

Oncotarget

Precision Medicine in SCLC: DLL3, ASC1, TTF-1, and Ki-67 Expression

November 6, 2024

This study presents an observational, cross-sectional analysis of 64 patients diagnosed with small cell lung cancer (SCLC) at a reference laboratory for thoracic pathology between 2022 and 2024.”BUFFALO, NY -... read more

Oncotarget

Immunotherapy Success in KRAS G12C Adenosquamous Pancreatic Cancer

November 4, 2024

Here, we present a case of metastatic ASCP with a KRAS G12C mutation refractory to multiple lines of systemic therapy, including platinum-based chemotherapy and targeted inhibition of KRAS G12C.”BUFFALO,... read more

Oncotarget

Tumor Dormancy Initiated by Lymphovascular Embolus

October 30, 2024

Both our experimental as well as observational studies indicate that in vivo lymphovascular tumor emboli and their in vitro spheroid equivalent initiate dormancy through these pathways.”BUFFALO, NY- October 30,... read more

Oncotarget

Complete Response to Encorafenib + Binimetinib in BRAF V600E-Mutant Tumor

October 29, 2024

This case report highlights the importance of full tumor genotyping to identify potentially actionable targets in rare tumors such as malignant glomus tumors.”BUFFALO, NY- October 29, 2024 – A new... read more

Oncotarget

Next-Gen Cell-Penetrating Antibodies for Tumor Targeting and RAD51 Inhibition

October 21, 2024

Overall, the data presented in this study affirm that humanizing 3E10 preserves its crucial biological properties essential for therapeutic efficacy.”BUFFALO, NY- October 21, 2024 – A new research paper was... read more