Tag: Colon Cancer

Oncotarget News

Figure 7: Immunological effect of Nerofe and DOX: CT26 murine model showing the immunological effect of Nerofe, DOX, and their combined treatment.

Transformation of Immunosuppressive mtKRAS Tumors Into Immunostimulatory Tumors by Nerofe and Doxorubicin

July 5, 2023

we demonstrated that the combination of Nerofe and DOX exerts a synergistic effect during mCRC treatment [...]”BUFFALO, NY- July 5, 2023 – A new research paper was published in Oncotarget's Volume... read more

Oncotarget

DPDT Anticancer Activity in Human Colon Cancer HCT116 Cells

June 26, 2023

Altogether, our results show that DPDT preferentially targets HCT116 colon cancer cells likely through DNA topoisomerase I poisoning.”BUFFALO, NY- June 26, 2023 – A new research paper was published in... read more

Figure 1: Retinol-mediated suppression of tumor-promoting IL-6 is disrupted in colon cancer-associated fibroblasts.

Oncotarget

Retinol Disruption and the Role of Vitamin A Metabolism in Colon Cancer

May 3, 2023

Retinoids are known to inhibit tumor-promoting IL-6 production.”BUFFALO, NY- May 3, 2023 – A new research perspective was published in Oncotarget's Volume 14 on April 26, 2023, entitled, “Disruption of... read more

Oncotarget

Behind the Study: New Clues for Targeting Drug Resistant Colon Cancers

March 8, 2021

Dr. Bruce Boman from the Helen F. Graham Cancer Center describes the findings in a study he helped author in Oncotarget titled, "The anti-cancer effect of retinoic acid signaling in... read more