Tag: kinase inhibitors

Oncotarget News

Figure 4: Depletion of DHX33 antagonizes GPS167-mediated cytotoxicity.

Anticancer Potential of CLK Kinase Inhibitors 1C8 and GPS167 via EMT and Antiviral Immune Response

May 20, 2024

we have characterized a pair of compounds that impact multiple processes that are relevant to cancer cell proliferation but also, and possibly more importantly, to metastasis [...].”BUFFALO, NY- May 20,... read more

Figure 1: PET scan at screening (A), 5 months (B) and 8 months on treatment (C). CDK9 INHIBITORS

Oncotarget

CDK9 Inhibitors: A Promising Combination Partner in Treating Hematological Malignancies

August 9, 2023

CDK9 inhibitors could play a role in future treatments of hematological diseases and could be a great ally when combined with other therapeutic approaches.” BUFFALO, NY- August 9, 2023 –... read more

Oncotarget

Oncotarget | Kinase Activity in Renal Cell Carcinoma, Benign Renal Tissue and in Response to Tyrosine Kinase Inhibitors

August 17, 2022

Thus, the presented findings might provide options to select the most promising TKI for individual RCC patients prior to initiation of TKI-therapies.”BUFFALO, NY- August 17, 2022 – A new research... read more

CancerOmicsNet: a multi-omics network-based approach to anti-cancer drug profiling

Oncotarget

Anti-Cancer Drug Profiling With CancerOmicsNet

May 19, 2022

BUFFALO, NY- May 19, 2022 – A new research paper was published in Volume 13 of Oncotarget, entitled, “CancerOmicsNet: a multi-omics network-based approach to anti-cancer drug profiling.”Researchers from Louisiana State... read more