paper spotlight Archives

Oncotarget News

Tracking cfDNA Release Dynamics During Colorectal Cancer Surgery

January 27, 2025

Taken together, our results suggest that in addition to physiological age, comorbidities and unfavorable clinical traits, intense surgical manipulation from the tumor's extent, may result in greater tissue damage and... read more

Oncotarget

Anti-Correlation Between KLRG1 and PD-1 in Tumor CD8 T Cells

January 21, 2025

The anti-correlation of PD-1 and KLRG1 expression in human tumor infiltrating CD8 T cells suggests the potential for combination therapy supra-additive benefits of anti-PD-1 and anti-KLRG1 therapies.”BUFFALO, NY - January... read more

Oncotarget

Pitfalls of FDA-Approved Germline Cancer Predisposition Tests

December 30, 2024

The FDA approval on September 29, 2023, for 'class III de novo' blood tests to assess hereditary cancer risk make widely available tests that may be obtained through a Direct... read more

Oncotarget

CT Radiomics and Body Composition for Predicting Hepatic Decompensation

December 9, 2024

This study reveals the potential for prognostic features in predicting hepatic decompensation in patients with PSC.”BUFFALO, NY - December 9, 2024 – A new research paper was published in Oncotarget's Volume... read more

Oncotarget

Mesenchymal Stem Cells in Cancer Immunotherapy: Promises and Challenges

December 3, 2024

MSCs hold great promise as a therapeutic tool in cancer immunotherapy due to their immunomodulatory properties, tumor-homing abilities, and potential as carriers for delivering therapeutic agents.”BUFFALO, NY - December 3,... read more

Oncotarget

Visualizing Radiological Data Bias with Persistence Images

November 25, 2024

Persistence images represent a powerful new tool in our ongoing efforts to visualize, understand, and mitigate biases in radiological data interpretation and AI model development.”BUFFALO, NY - November 25, 2024 –... read more

Oncotarget

Reducing Bias in Radiology with Topological Data Analysis

November 18, 2024

By providing a more comprehensive, robust, and interpretable framework for analyzing medical imaging data, TDA has the potential to enhance the accuracy and fairness of radiological assessments.”BUFFALO, NY - November... read more

Oncotarget

Navigating Bias in AI-Driven Cancer Detection

November 11, 2024

As we eagerly adopt Al models, we need to take a moment to think about the potential biases that they may contain.”BUFFALO, NY - November 11, 2024 – A new editorial... read more

Oncotarget

Immunotherapy Success in KRAS G12C Adenosquamous Pancreatic Cancer

November 4, 2024

Here, we present a case of metastatic ASCP with a KRAS G12C mutation refractory to multiple lines of systemic therapy, including platinum-based chemotherapy and targeted inhibition of KRAS G12C.”BUFFALO,... read more

Oncotarget

Complete Response to Encorafenib + Binimetinib in BRAF V600E-Mutant Tumor

October 29, 2024

This case report highlights the importance of full tumor genotyping to identify potentially actionable targets in rare tumors such as malignant glomus tumors.”BUFFALO, NY- October 29, 2024 – A new... read more