Tag: STAT3

Oncotarget News

Figure 1: (A) Canonical STAT3 activation pathway. (B) WP1066 and TTI-101, examples of small molecule STAT3 inhibitors that are cell penetrant.

STAT3 as a Target in H3K27M-mutant DMGs

October 9, 2023

Children diagnosed with these tumors have [...] a median survival of approximately 12 months.” BUFFALO, NY- October 9, 2023 – A new editorial perspective was published in Oncotarget's Volume 14 on... read more

Figure 3: Cytokine expression and cell viability upon mRNA silencing of STAT3 isoforms

Oncotarget

Differential Silencing of STAT3 Isoforms Leads to Changes in STAT3 Activation

April 26, 2023

Our study emphasizes the importance of distinguishing between STAT3α and STAT3β proteins and their active forms when discussing STAT3-related cancer diagnosis and therapy.”BUFFALO, NY- April 26, 2023 – A new... read more

Whitney Henry; a recent graduate from the lab of Alex Toke

Oncotarget

Behind the Study: LINC00520 and Breast Cancer

March 22, 2021

The Behind the Study series transcribes videos of researchers elaborating on their papers published in Oncotarget. Visit the Oncotarget YouTube channel for more insights... read more

Oncotarget

Behind the Study: Critical Role STAT3 Plays in Glioma-initiating Cells

February 8, 2021

The head chair of pathology and a graduate research assistant from the University of Tennessee Health Science Center detail their paper published in Oncotarget titled, "The critical role that STAT3... read more