Tag: Stem Cells

Oncotarget News

Mesenchymal Stem Cells in Cancer Immunotherapy: Promises and Challenges

December 3, 2024

MSCs hold great promise as a therapeutic tool in cancer immunotherapy due to their immunomodulatory properties, tumor-homing abilities, and potential as carriers for delivering therapeutic agents.”BUFFALO, NY - December 3,... read more

Oncotarget

TP53 Mutated AML: Transplant or No Transplant

October 11, 2024

In summary, this study reported improved survival when allo-HTC was performed in CR1 versus after later lines of therapy.”BUFFALO, NY- October 11, 2024 – A new editorial was published in... read more

Oncotarget

miR-10b Inhibition: A Strategy for Treating Metastatic Breast Cancer

August 28, 2024

We have developed a nanodrug, termed MN-anti-miR10b, that delivers anti-miR-10b antisense oligomers to cancer cells.”BUFFALO, NY- August 28, 2024 – A new research paper was published in Oncotarget's Volume 15... read more

Figure 3: (A) Simulations of the reaction-diffusion model (solid lines) and measured follicle length (solid circles). (B) The function a(x) describing the pro-survival factor released by the regenerative stem cell pool. The inset shows a schematic of a hair follicle regressing slower as it gets shorter and closer to higher values of the pro-survival factor modeled with the function a(x) and released by the regenerative stem cells.

Oncotarget

Apoptotic Cells May Drive Cell Death in Hair Follicles During Regression Cycle

October 23, 2023

Revealing the stem cell niche self-renewal dynamics is important not only for understanding tissue homeostasis but also for understanding the initiation of cancer [7].”BUFFALO, NY- October 23, 2023 – A... read more

Oncotarget

Behind the Study: Wnt Signaling Perturbs Spermatogenesis

April 12, 2021

Behind the Study is a series of transcribed videos from researchers elaborating on their recent oncology-focused studies published in Oncotarget. A new Behind the Study is released each Monday.... read more

Oncotarget

Behind the Study: Critical Role STAT3 Plays in Glioma-initiating Cells

February 8, 2021

The head chair of pathology and a graduate research assistant from the University of Tennessee Health Science Center detail their paper published in Oncotarget titled, "The critical role that STAT3... read more